KO‘KRAK BEZI SAROTONI RETSEPTORLARI
Keywords:
Kalit so‘zlar: Estrogen retseptorlari, ER, ko‘krak bezi saratoni, ER signalizatsiyasi,, terapevtik maqsadlar. Spirtli ichimliklarni ichish koʻkrak bezi saratoni asorati, ko‘krak bezi.Abstract
Steroid birikmalar guruhiga mansub estrogenlar fiziologik va kasallik jarayonlarida, asosan, estrogen retseptorlari bilan o‘zaro ta’sir qilish orqali muhim rol o‘ynaydi. Anormal ER signalizatsiya ko‘krak saratoni (miloddan avvalgi), global ayollarda eng tez-tez tashxis saraton biri va ayol saraton bilan bog‘liq o‘lim ikkinchi sabab, shu jumladan, turli saraton, olib kelishi mumkin. Kichik o‘lchamdagi agressiv karsinomalarni tashxislash masalasi butun dunyoda dolzarb va o‘z vaqtida bo‘lib, ushbu tadqiqot uchun turli xil biologik RMJ subtiplari bo‘lgan bemorlarda mikrokarsinomalarning eng xarakterli rentgenologik va sonografik xususiyatlarini izlash uchun asos bo‘lib xizmat qildi. So‘nggi o‘n yilliklarda radiatsiya diagnostikasi tomonidan to‘plangan, ba’zi hollarda mammografiya paytida aniqlangan o‘zgarishlarni talqin qilish qiyin bo‘lishi mumkin. rentgen nazorati ostida sut bezlari shakllanishining stereotaktik biopsiyasini o‘tkazish qobiliyati ixtisoslashgan onkologiya muassasasining ambulatoriya – poliklinika bo‘limining muvaffaqiyatli ishlashining muhim omillaridan biridir.
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