INVESTIGATION OF ENDOTHELIAL AND RENAL DYSFUNCTION IN PATIENTS WITH STABLE ANGINA PECTORIS AND ASSESSMENT OF THEIR RELATIONSHIP

Abstract

Material and research methods. 42 patients with coronary heart disease (CHD)
aged 45 to 70 years (mean age 63.5±4.5 years) were examined. The first group
consisted of 22 people, including 15 men and 7 women (mean age of patients 56.4±7.5
years) with functional class II coronary heart disease and without kidney damage. The
second group included 20 people (14 and 6 women), mean age 62.0±5.5 years, with
functional class III ischemic heart disease and no primary kidney disease in men. 10
people of the first group and 16 people of the second group suffered from hypotonic
52 diseases, 8 and 12, respectively, history of diabetes. All patients underwent a general
clinical examination with an assessment of the content of cystatin and calcium in the
blood. The glomerular filtration rate calculates the plasma concentration of cystatin
using the formula of Hoek et al. (2003): GFR [mL/min/1.73m2] = (80.35/cystatin C
[mg/mL]) - 4.32.