INFLUENCE OF ANTIHYPERTENSIVE DRUGS ON INSULIN RESISTANCE AND LIPID SPECTRUM INDICATORS
Keywords:
Key words: Arterial hypertension, metabolic syndrome, lipid spectrum, HOMA index , insulin resistance.Abstract
Relevance: The mechanism of development of arterial hypertension and insulin
resistance in overweight individuals is of great importance in the tactics of choosing
drugs, dose and duration of use, as well as the combination of antihypertensive drugs,
statins , biguanides , insulin drugs and hepato- and cardioprotectors . Hence,
antihypertensive drugs, Losartan and Nebivolol , used to treat patients with excess body
weight and/or insulin resistance, meet the following requirements: effectively reduce
blood pressure throughout the day, do not have an adverse effect on carbohydrate, lipid,
purine metabolism, have an organoprotective effect, and reduce the risk MTR
development.
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