VIFERON USE IN CHILDREN
Keywords:
Keywords: acute respiratory viral infection, mucous membranes of the upper respiratory tract, local immunity, immunomodulatory therapy, antioxidants, adult patientsAbstract
The results of a study of the clinical and immunological effectiveness of local use of a recombinant preparation of interferon α-2β (Viferon® ointment) for acute respiratory viral infection (ARVI) of various etiologies in 100 young children are presented. It was shown that the use of a local ointment form of the drug made it possible to reduce the duration of the severity of symptoms of the disease and achieve the elimination of pathogens at the entrance gates of ARVI without systemic effects on the child’s immune system. The article provides a comparative analysis of the results of clinical and laboratory studies performed at 10 different medical institutions based on the principles and methodology of evidence-based medicine, which confirmed the reliability of the clinical effectiveness of the use of the drug Viferon® (suppositories, gel/ointment) in the treatment of influenza and acute respiratory viral infections (ARVI) in adult patients. The algorithm included assessment of the antiviral, immunomodulatory, anti-inflammatory, antioxidant effects of the drug in prospective open randomized placebo-controlled clinical and immunological studies and retrospective analysis in accordance with the Rules of Good Clinical Practice.
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