АНАЛИЗ ЛАБОРАТОРНЫХ ИЗМЕНЕНИЙ ПРИ АУТОИММУННОЙ ГЕМОЛИТИЧЕСКОЙ АНЕМИИ
Keywords:
Key words: autoimmune hemolytic anemia, severity, hematological parameters, laboratory abnormalities, hemolysis.Abstract
Material and methods: The study was conducted with the participation of 93 patients with primary autoimmune hemolytic anemia (AIHA) and 97 healthy donors without a history of autoimmune diseases. The selection of patients was carried out when applying to the Republican Specialized Scientific and Practical Medical Center of Hematology (RSNPMCG) from 2018 to 2022 yy.
The subjects' hematological blood parameters were analyzed on an automatic hematological analyzer "Sysmex" using test systems from the company "HUMAN, Germany". Mathematical calculations of the obtained results were carried out using the statistical software package Microsoft Office Excel-2019.
References
Berentsen S., Barcellini W. Autoimmune hemolytic anemias //New England Journal of Medicine. – 2021. – Т. 385. – №. 15. – С. 1407-1419.
Yeruva S. L. H. et al. Pernicious anemia with autoimmune hemolytic anemia: a case report and literature review //Case Reports in Hematology. – 2016. – Т. 2016.
Hosoba S. et al. Successful treatment of severe immune hemolytic anemia after allogeneic stem cell transplantation with bortezomib: report of a case and review of literature //Transfusion. – 2015. – Т. 55. – №. 2. – С. 259-264.
Taherifard E. et al. Hematologic autoimmune disorders in the course of COVID-19: a systematic review of reported cases //Hematology. – 2021. – Т. 26. – №. 1. – С. 225-239.
Bernard C. et al. Thymoma associated with autoimmune diseases: 85 cases and literature review //Autoimmunity reviews. – 2016. – Т. 15. – №. 1. – С. 82-92.
Lecouffe-Desprets M. et al. Venous thromboembolism related to warm autoimmune hemolytic anemia: A case–control study //Autoimmunity reviews. – 2015. – Т. 14. – №. 11. – С. 1023-1028.
Haw A., Palevsky H. I. Pulmonary hypertension in chronic hemolytic anemias: Pathophysiology and treatment //Respiratory medicine. – 2018. – Т. 137. – С. 191-200.
Жахонов, А., Саидов, А., & Маткаримова, Д. (2023). Вклад полиморфного гена IL17A (rs2275913) в механизмы формирования аутоиммунной гемолитической анемии. Наука и инновация, 1(15), 77–78.
Жахонов, А., Саидов, А., & Маткаримова, Д. (2023). Анализ клинико-лабораторных проявлений аутоиммуной гемолитической анемии. Академическая международная конференция по междисциплинарным исследованиям и образованию, 1(12), 40-42.
Matkarimova D. S. et al. Association of allelic polymorphism of the proinflammatory cytokine gene VEGFA (rs2010963) with the development and severity of immune microthrombovasculitis. – 2021.
